MLB picks, predictions, best bets for Sunday, June 8: Yankees vs Red Sox, Cardinals vs Dodgers and more

Many Sundays in MLB don't feature elite matchups like the New York Yankees vs the Boston Red Sox and the Los Angeles Dodgers vs the St. Louis Cardinals. Thus, it will be a thrilling watch for viewers.

To make the job easier for those interested in betting, we have jotted down predictions for all interesting matchups on Sunday, along with the best bets to be placed for the game.

Without further ado, let's get to them.

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Yankees vs Red Sox

Predicted Score: Yankees 5, Red Sox 3

Best Bet:

• Under 8 runs total.
• Yankees ML (-219)

The contest features an elite pitching duel between Carlos Rodón for New York vs. Hunter Dobbins for Boston. Both teams have split the first two games of the series with a flurry of runs, making the rubber game a must-watch. Yankees should be the focus for bettors for this game.

Cardinals vs Dodgers

Predicted Score: Dodgers 4, Cardinals 2

Best Bet:

• Pick Dodgers ML (-144)
• Under 7.5 runs

Clayton Kershaw is on the mound, and while he hasn't been his best in 2025, he has elite pitches that can take the young Cardinals unit apart. Also, it's rare to see the Dodgers get swept, thus, the offense should come strong after poor outings in the first two games of the series.

Cubs vs Tigers

Predicted Score: Cubs 5, Tigers 3

Best bet:

• Pick: Cubs to win

Cubs boast a better rotation, and with Cade Horton on the mound, the team has been relatively successful. Expect strong offensive output from Kyle Tucker & Co. against Tigers' Jack Flaherty.

Guardians vs Astros

Predicted Score: Guardians 5, Astros 3

Best Bet:

• Pick: Guardians to win

Guardians have the home-field advantage, and the elite offense of José Ramírez & Co. should be too much for the Astros. Tanner Bibee will be on the mound for Cleveland while Brandon Walter makes his season debut for the Astros.

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Giants vs Braves

Predicted Score: Giants 5, Braves 3

Best Bet:

• Pick: Giants ML

The Giants will have Landen Roupp while the Braves place Spencer Strider on the mound. Strider has struggled relatively, and the Giants' lineup won't be easy for him to get by. Expect a close game, but the Giants will emerge victorious.

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Here are a few more interesting matchups with predictions:

Twins vs Blue Jays

Predicted Score: Twins 6, Blue Jays 4

Rays vs Marlins

Predicted Score: Marlins 4, Rays 3

White Sox vs Royals

Predicted Score: Royals 6, White Sox 2

Rockies vs Mets

Predicted Score: Mets 7, Rockies 4

Edited by Dipayan Moitra