Cagliari vs Pisa Prediction and Betting Tips | December 21st 2025

The Italian Serie A returns with a fresh set of fixtures as Cagliari play host to Pisa at the Unipol Domus on Sunday. This will be the first meeting between the two teams since April 2023, when they played out a goalless draw in their Serie B clash.

Cagliari were sent crashing down to earth last Saturday as they fell to a 2-1 defeat against Atalanta when the two sides squared off at the Gewiss Stadium.

Before that, Fabio Pisacane’s men secured a 1-0 home victory over AS Roma on December 7, a result which saw their run of 10 straight games without a win in all competitions come to an end.

Cagliari have picked up 14 points from their 15 Serie A matches so far to sit 15th in the league standings, level on points with Genoa and Parma.

On the other hand, Pisa were left empty-handed once again last time out when they were beaten 1-0 by Lecce at the Via del Mare.

Eusebio Di Francesco’s men have lost three consecutive matches, suffering defeats against Inter Milan, Parma and Lecce, having gone unbeaten in the six games preceding this run (1W 5D).

Pisa have won just one of their 15 Serie A matches so far while losing seven and claiming seven draws to collect 10 points and sit 19th in the standings, four points above rock-bottom Fiorentina.

Cagliari vs Pisa Head-To-Head and Key Numbers

• Cagliari hold the upper hand in the history of this fixture, having picked up one win and two draws from the previous three meetings between the two teams.
• Pisa are without a win in their last eight away games across all competitions, losing four and picking up four draws since August’s penalty-shootout victory over Cesena on August 17.
• Cagliari have failed to win four of their most recent five Serie A home matches, losing three and claiming one draw since September 13.
• Pisa have failed to find the back of the net in their last three matches, while conceding four across the three games since a 2-2 draw against Sassuolo on November 24.

Cagliari vs Pisa Prediction

It has been a difficult return to the Italian top flight for Pisa, who have struggled to impose themselves in the big leagues and are early candidates to go down.

Cagliari have also struggled for results this season, but they boast a superior squad on paper, and we fancy them to come out on top in front of their home supporters.

Prediction: Cagliari 2-0 Pisa

Cagliari vs Pisa Betting Tips

Tip 1: Result - Cagliari to win

Tip 2: Over 2.5 goals - No (There have been fewer than three goals scored in four of Pisa’s last five games)

Tip 3: Over 4.5 cards - No (There have also been fewer than five bookings in five of the visitors’ last seven outings)

Edited by Peter P