Today’s 5 Best MLB Prop Bets: Strikeouts, Total Runs, and Moneyline Picks for Blue Jays vs Dodgers World Series Game 4 - October 28, 2025

After an over 6-hour, 18-inning marathon in Game 3 that drained every ounce of bullpen depth from both sides, the Dodgers and Blue Jays return for a crucial Game 4 at Dodger Stadium.

Los Angeles now leads the series 2–1, but fatigue is setting in fast, the Dodgers used 10 pitchers last night, while Toronto’s offense looked sharper with every inning.

Tonight’s matchup features two elite arms in Shohei Ohtani and Shane Bieber, but behind the surface, tired relievers, worn-down lineups, and desperate managerial decisions create a goldmine for prop bettors looking to capitalize on a high-variance game script.

Note: Odds are set by DraftKings Sportsbook and are subject to change. No outcome can be guaranteed when betting on sports.

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Today’s 5 Best MLB Prop Bets for Blue Jays vs Dodgers World Series Game 4

1. Shane Bieber: Outs Recorded Over 14.5 (−168)

Bieber’s over on outs recorded is a smart play given the Blue Jays’ desperate need for length from their starter.

The veteran righty has quietly been consistent this postseason, holding opponents to limited damage while working deep into games when Toronto needs him most.

After the bullpen threw over 230 pitches in Game 3, John Schneider simply can’t afford a short outing, and the Jays will likely let him handle at least five innings before turning it over to the pen.

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#2. Vladimir Guerrero Jr.: Hits + Runs + RBIs 2+ (−107)

No hitter has been more locked in this postseason than Vladimir Guerrero Jr. He’s batting over .400 in October and has been at the center of nearly every Blue Jays rally, posting a 1.200+ OPS with multiple extra-base hits.

Guerrero’s ability to drive in runs or score himself makes this prop versatile even a single plus a run gets you halfway there.

With Ohtani’s occasional tendency to leave splitters up and the Dodgers’ bullpen running on fumes, Guerrero’s odds to rack up at least two combined stats are simply too short to ignore. He’s the heartbeat of Toronto’s offense right now.

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#3. Shohei Ohtani: Strikeouts Over 6.5 (−117)

Ohtani has been sensational on the mound this postseason, and the over on his strikeouts remains one of the most reliable plays available.

Across two October starts, he’s tallied 19 strikeouts in just 12 innings, and his slider-splitter combo has completely baffled right-handed hitters.

The Blue Jays tend to chase offspeed pitches below the zone exactly the zone Ohtani thrives in.

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#4. Total Runs: Over 8 (−111)

Both teams’ bats are heating up, and the over 8 looks very much in play here. The Dodgers have averaged 4.7 runs per game this postseason, while the Blue Jays’ offense has exploded for double-digit hits in multiple games.

Add in the bullpen exhaustion from last night’s marathon and this game sets up for fireworks late.

Dodger Stadium’s mild weather and carry-friendly night conditions only strengthen the over angle especially if either lineup jumps on early fastballs before pitchers settle in.

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#5. Blue Jays Moneyline (+176)

At +176, Toronto is a live underdog in this spot. Yes, they’re facing Ohtani, but fatigue changes everything, the Dodgers’ bullpen was stretched to its absolute limit in Game 3, and that could open the door for Blue Jays' red-hot bats.

Blue Jays has already proven they can hit elite pitching, and with Bieber giving them stability early, the value on this line is undeniable.

If they can scratch out a few runs early and force Ohtani’s pitch count up, this price tag suddenly looks like a gift.

Edited by Shubham Soni