Mexico vs Uruguay Prediction and Betting Tips | November 16th 2025

Mexico and Uruguay return to action on Saturday when they square off in an international friendly fixture at the Estadio Corona. This will be the first meeting between the two teams since June 2024, when Uruguay cruised to a 4-0 victory in a similar friendly fixture.

Mexico played out a 1-1 draw with Ecuador last time out when German Berterame and Jody Alcivar netted for either side to force a share of the spoils on October 15.

Javier Aguirre’s men have failed to win any of their four friendly matches since their Gold Cup triumph in July, claiming three draws and losing once in that time.

Next up for Mexico is the stern challenge of an opposing side who have won five of their most recent six encounters, with a 3-1 victory in June 2016 being the exception.

On the other hand, Uruguay maintained their fine run of results last time out as they picked up a 2-1 victory over Uzbekistan at the Stadium Hang Jebat on October 13.

Before that, Marcelo Bielsa’s side closed out their 2026 FIFA World Cup qualifying campaign with two wins and one draw from their final three games, before claiming a 1-0 friendly victory over Dominican Republic on October 10.

Uruguay picked up 28 points from their 18 matches in the World Cup qualifiers to finish fourth in the group standings and seal a fifth straight appearance in the global tournament.

Mexico vs Uruguay Head-To-Head and Key Numbers

• The results have been split right down the middle in the history of this fixture, with Mexico and Uruguay both claiming eight wins from their previous 23 encounters.
• Uruguay are on a run of three consecutive victories over Aguirre's men, scoring 11 goals and keeping two clean sheets since a 3-1 defeat in June 2016.
• Mexico have lost just one of their last 11 matches across all competitions, while picking up six wins and four draws since June 7.
• Uruguay have failed to win seven of their last eight away games since September 2024, losing twice and claiming five draws in that time.

Mexico vs Uruguay Prediction

Mexico and Uruguay head into the weekend in contrasting form, with Aguirre’s men failing to win their most recent four matches.

Uruguay are on a dominant run in this fixture, and given their current form, we are backing them to come away with the desired result at the Estadio Corona.

Prediction: Mexico 1-2 Uruguay

Mexico vs Uruguay Betting Tips

Tip 1: Result - Uruguay to win

Tip 2: Over 2.5 goals - Yes (There have been at least three goals scored in four of the last five meetings between the two sides)

Tip 3: Over 4.5 cards - No (There have also been fewer than five bookings in six of their last seven encounters)

Edited by Peter P