Who plays on 'Thursday Night Football' tonight? Time, TV channel, schedule, live stream for NFL Week 2 game

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The Bills and Lions kicked off their campaigns with hard-fought wins in Week 1. They'll turn their fiery attacks on each other in Week 2, taking hold of the contentious Highmark Stadium grass under the lights.

Buffalo's offense looked lively in its season-opening conquest of the Texans, amassing four touchdowns en route to a 36-31 victory. Josh Allen accounted for all four scores, continuing his tradition of authoring up explosive first-game performances.

Detroit finished its match with an identical 1-0 record to the Bills. The mood around the Motor City was far less enthused, however. The Lions struggled to put away a Saints side it was expected to dispose of easily, only hanging on after New Orleans missed its two-point conversion attempt in overtime. Dan Campbell's side still fancies itself a contender after Week 1. But it will be looking for a more assured performance in Week 2.

The Bills and Lions will take center stage on "Thursday Night Football." Here's how you can watch.

Who plays on 'Thursday Night Football' tonight?

  • Matchup: Bills vs. Lions
  • Location: Highmark Stadium, Buffalo

The Bills will host the Lions on "Thursday Night Football" from Highmark Stadium in Buffalo.

What time is the NFL game on tonight?

  • Date: Thursday, September 17
  • Time: 8:15 p.m. ET

Kickoff of Bills vs. Lions is scheduled for 8:15 p.m. ET on Thursday, September 16.

What channel is 'Thursday Night Football' on?

"Thursday Night Football" will air exclusively on Prime Video with Al Michaels (play-by-play) and Kirk Herbstreit (color commentator) on the call. 

Amazon Prime offers a free trial, allowing new users to tune into Thursday's game and everything the service has to offer before commitment.

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