Philadelphia 76ers vs OKC Thunder Prediction and Betting Tips - Dec. 28 | 2025-26 NBA Season

NBA fans are set for a six-game slate on Sunday, highlighted by the season’s first meeting between Eastern Conference contender Philadelphia 76ers (16-13) and defending champion OKC Thunder (26-5).

Both teams enter the matchup riding two-game losing streaks and will be looking to get back in the win column.

Here’s a preview of this Philadelphia 76ers vs OKC Thunder game, scheduled to tip off at 4:30 p.m. ET at Paycom Center in Oklahoma.

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Philadelphia 76ers vs OKC Thunder Preview and Odds

Moneyline: 76ers (+585) vs Thunder (-950)

Spread: 76ers +14.5 (-110) vs Thunder -14.5 (-110)

Total (O/U): 76ers o225.5 (-110) vs Thunder u225.5 (-110)

Editor's note: The odds could change close to the game. The odds listed were as per available information at the time of writing.

Philadelphia 76ers vs OKC Thunder preview

Both teams have navigated health concerns, though those issues have not translated into victories.

Philadelphia fell to 0-4 this season in games where Joel Embiid, Tyrese Maxey and Paul George all played following a loss to the Chicago Bulls, while OKC remains winless with its full starting lineup available.

While that trend is worth monitoring, injury problems continue. Embiid, Kelly Oubre Jr. and Trendon Watford are out for the 76ers, while Jaylin Williams and Ousmane Dieng remain sidelined for the Thunder.

Defensively, both squads rank among the league’s elite, with OKC sitting No. 2 and Philadelphia No. 3 in defensive rating for December.

The Thunder have now lost consecutive games for the first time this season and have dropped four of their last six after opening the year 24-1, though OKC is a perfect 4-0 against Eastern Conference opponents.

This matchup marks the second game of a five-game road trip for Philadelphia, and it will be worth watching how the 76ers’ league-third-ranked shot blocking holds up against OKC’s double-big lineup.

Philadelphia 76ers vs OKC Thunder betting tips

• Shai Gilgeous-Alexander O/U 31.5 points – Take the over.
• Jalen Williams O/U 18.5 points – Take the over.
• Tyrese Maxey O/U 27.5 points – Take the under.
• Paul George O/U 16.5 points – Take the over.

Philadelphia 76ers vs OKC Thunder prediction

This shapes up as an intriguing matchup between two teams led by dynamic young talent, though the healthier Thunder present a significant challenge. OKC’s defense should be able to contain a Philadelphia offense that has ranked near the bottom of the league in December.

Our prediction: Thunder win by 13.

Edited by John Ezekiel Hirro