OKC Thunder vs San Antonio Spurs Prediction and Betting Tips - Dec. 23 | 2025-26 NBA Season 

The OKC Thunder will be taking on the San Antonio Spurs for the second night of a back-to-back in the 2025-2026 NBA regular season. It will be a marquee matchup for both squads as they are among the top teams in the stacked Western Conference.

The Thunder is coming off a win against the Memphis Grizzlies, which served as their bounce-back victory after losing to the Minnesota Timberwolves in their previous game. The team still owns the best record in the NBA with a 26-3 record.

Meanwhile, the Spurs have won their last six games and sit in second place in the Western Conference standings with a 21-7 record. San Antonio is among the three teams that beat the Thunder this season.

Here is the preview of the Thunder-Spurs clash set inside the Frost Bank Center in San Antonio. Tip-off is set at 9:30 p.m. Eastern time.

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OKC Thunder vs San Antonio Spurs odds

Moneyline: Thunder -260 vs Spurs +235

Spread: Thunder -6.5 (-105) vs Spurs +7 (-110)

Total (O/U): Thunder -110 (o234.5) vs Spurs -110 (u234.5)

Editor's note: The odds could change close to the game. The odds listed were as per available information at the time of writing.

OKC Thunder vs San Antonio Spurs preview

The OKC Thunder will be led by the reigning MVP Shai Gilgeous-Alexander, who is averaging 32.5 points, 4.7 rebounds, and 6.4 assists per game this season. Gilgeous-Alexander put up 31 points, 10 rebounds, and eight assists in their win against the Grizzlies.

Jalen Williams will be backing him up as he averages 17.6 points per game. Williams had 24 points and 10 rebounds against the Grizzlies.

On the other hand, the Spurs will be leaning on Victor Wembanyama as he is carrying the team's offense this season with 24.4 points, 12.3 rebounds, and 3.3 blocks per game. Wembanyama played in their previous game versus the Washington Wizards, where he chipped in 14 points and 12 rebounds.

De'Aaron Fox is the next option with averages of 22.4 points and 6.1 assists per game.

OKC Thunder vs San Antonio Spurs betting tips

• Shai Gillgeous-Alexander O/U 32.5 points – Take the under.
• Jalen Williams O/U 17.5 points– Take the over.
• Victor Wembanyama O/U 24.5 points– Take the over.
• De'Aaron Fox O/U 22.5 points– Take the under.

OKC Thunder vs San Antonio Spurs prediction

We predict a win for the Thunder in a tight matchup against the Spurs. The Thunder will be more motivated for the game to avenge their loss in the NBA Cup against the Spurs. Jalen Williams has also impressed in his previous game, indicating that he is getting his rhythm back with the Thunder.

Our prediction: Thunder win by 5.

Edited by Rob Andrew Lo