Mets vs. Phillies: Game 2 prediction, odds, injuries, and picks - June 21, 2025

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The Mets are looking to stave off their calamitous spiral as they take on the Phillies in Game 2 of their three-game series at Citizens Bank Park. Carlos Mendoza's contingent has now lost seven-straight games and have surrendered the lead of the NL East to Philadelphia after Friday night's 10-2 loss.

Griffin Canning would have the tough task of limiting the Philly offense amid an expected raucous reception on the road. In three starts in June, Canning has posted a 1-1 record and a 5.74 ERA across 15 2/3 innings.


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Mets vs. Phillies recent form and records

The Metropolitans are on the brink of collapse, having been embroiled in a seven-game skid that started on June 13 against the Rays. They now possess a 45-31 record and the second spot in the NL East.

On the other hand, the Phils were gifted the top spot in the division thanks to their consistent gameplay despite superstar Bryce Harper's absence and the current downfall of the Mets. The squad has won eight of its last 10 games as it has drastically improved its record to 46-30.


Mets vs. Phillies odds

Money Line: NYM (-101), PHI (-108)

Run Spread: NYM -1.5 (+142), PHI +1.5 (-173)

Total Runs: O 10.5 (+105), U 10.5 (-127)


Mets vs. Phillies injuries

NYM injury report

  • Nick Madrigal (3B): 60-day IL (shoulder)
  • Kodai Senga (SP): 15-day IL (hamstring)
  • Mark Vientos (3B): 10-day IL (hamstring)
  • Sean Manaea (SP): 60-day IL (oblique)
  • Jose Siri (CF): 10-day IL (tibia)
  • Frankie Montas (SP): 60-day IL (lat)
  • Drew Smith (RP): 60-day IL (elbow)
  • A.J. Minter (RP): 60-day IL (lat)
  • Jessie Winker (LF): 10-day IL (oblique)
  • Brooks Raley (RP): 60-day IL (elbow)
  • Tylor Megill (SP): 15-day IL (elbow)

PHI injury report

  • Aaron Nola (SP): 15-day IL (ankle)
  • Bryce Harper (1B): 10-day IL (wrist)

Blue Jays vs. Phillies projected lineup

NYM projected lineup

  • Francisco Lindor (SS)
  • Brandon Nimmo (LF)
  • Juan Soto (RF)
  • Pete Alonso (1B)
  • Jeff McNeil (2B)
  • Starling Marte (DH)
  • Brett Baty (3B)
  • Tyrone Taylor (CF)
  • Francisco Alvarez (C)
  • Griffin Canning (SP, 6-3 | 3.80 ERA | 63 K)

PHI projected lineup

  • Trea Turner (SS)
  • Kyle Schwarber (DH)
  • Alec Bohm (3B)
  • Nick Castellanos (RF)
  • Max Kepler (LF)
  • J.T. Realmuto (C)
  • Bryson Stott (2B)
  • Otto Kemp (1B)
  • Brandon Marsh (CF)
  • Mick Abel (SP, 2-0 | 2.21 ERA | 17 K)

Blue Jays vs. Phillies picks and game prediction

The game is almost pegged as evens by bookmakers. However, given the form that the two squads are on, there is more upside in picking Philadelphia in the battle of the NL East juggernauts.

Run Line: PHI +1.5 (-173)

Total Runs: O 10.5 (+105)

Prediction: PHI wins, 8-5

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About the author

Daniel Santiago

Daniel Santiago is a journalist who has been reporting on baseball at Sportskeeda since 2022. He was drawn towards the sport after the underlying statistics and the analysis surrounding it grabbed his attention.

Daniel particularly enjoys furnishing reports about historic events in baseball and analyzing the game through a statistic-based outlook, based on Fangraphs and Baseball-Reference. This is in line with how he enjoyed watching baseball as a pastime. As a writer, he is very particular about cross-checking from reputable sources and doing his due diligence.

He became a lifelong Hideki Matsui fan after his exploits in the 2009 World Series for the New York Yankees. Among the current generation, Daniel's favorites include Shohei Ohtani and Jung Hoo Lee. Daniel is a huge follower of Asian baseball and both Ohtani and Lee have been in the top echelon of their respective leagues during their time with the NPB and KBO.

His favorite moment as a baseball fan was the final at-bat of the 2023 World Baseball Classic between Shohei Ohtani and Mike Trout. He believes there aren't many words to fittingly describe the intensity of the moment.

As an avid sports fan, Daniel watches other sports and Esports when not writing about baseball.

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