ZEISS supports the transition of spatial biology to clinical research

Article content

mIF staining reagents

Article content

The OmniVUE™ reagents from our partner Ultivue leverage advanced DNA-based amplification technology designed for high specificity and dynamic range, which can be optimally recorded with the ZEISS Axioscan 7 spatial biology. Ultivue offers ready-to-use validated assays paired with co-optimized analysis algorithms, eliminating the need for assay development and providing instructive data as much as three times faster than competing technologies. The improved instrument and workflow are fully compatible with a broad range of assays, including various mIF reagents, standard IHC, and H&E. Samples stained with different assays can easily be imaged automatically in the same batch.

Article content

Fully automated image analysis

Article content

The integrated solution by our partner Mindpeak makes image analyses for mIF samples as straightforward as for scoring of standard immunohistochemistry (IHC). Mindpeak’s leading technology for clinical-grade IHC image analysis and their streamlined cloud platform now enable the efficient analysis of IHC and mIF-stained tissue images generated by ZEISS Axioscan 7 spatial biology. Spatial biology assays can be paired with pre-optimized analytics that are automatically run after image acquisition, enabling efficient review processes and significantly accelerating the time to results.

Article content

Article content

Services for advanced lab automation

Article content

The new spatial biology workflow improves consistency and operational efficiency through an intuitive workflow manager software. Customization services are available to adapt the workflow to individual laboratory processes and to support integration with Laboratory Information Management Systems (LIMS).

Article content

AI-powered scanning and image analysis routines can be fully automated, documented, and controlled to meet lab-specific requirements, reducing the need for manual steps and supporting increased productivity and reproducibility. This enables spatial biology assays to be implemented as part of routine applications, even at high volumes ranging from hundreds to thousands of samples per day.

Article content

The solution is available both as a standalone offering and as an upgrade for existing ZEISS Axioscan 7 systems, providing flexible options for implementation and enhanced operational efficiency.

Article content

Article content

For more information, click here.

Article content

Article content

Press contact
ZEISS Research Microscopy Solutions
Vybhav Sinha
Phone: +49 3641 64 3949
Email: [email protected]

Article content

www.zeiss.com/newsroom

Article content

Article content

About ZEISS
ZEISS is an internationally leading technology enterprise operating in the fields of optics and optoelectronics. In the previous
fiscal year, the ZEISS Group generated annual revenue around 11 billion euros in its four segments Semiconductor Manufacturing Technology, Industrial Quality & Research, Medical Technology and Consumer Markets (30 September 2024).

Article content

For its customers, ZEISS develops, produces and distributes highly innovative solutions for industrial metrology and quality assurance, microscopy solutions for the life sciences and materials research, and medical technology solutions for diagnostics and treatment in ophthalmology and microsurgery. The name ZEISS is also synonymous with the world’s leading lithography optics, which are used by the chip industry to manufacture semiconductor components. There is global demand for trendsetting ZEISS brand products such as eyeglass lenses, camera lenses and binoculars.