Minnesota Timberwolves vs New York Knicks Prediction and Preview - Nov. 5 | 2025-26 NBA Season

There are 11 games on the schedule for Wednesday, including the Minnesota Timberwolves vs. New York Knicks matchup at Madison Square Garden. Julius Randle is back in the Big Apple, while Karl-Anthony Towns reunites with his former teammates.

The Timberwolves are navigating through the early parts of the season without Anthony Edwards, who is dealing with a hamstring injury. They enter Wednesday's game on a two-game winning streak and will look to sweep their three-game road trip.

Meanwhile, the Knicks began their seven-game homestand with back-to-back wins against the Chicago Bulls and Washington Wizards. Jalen Brunson has been putting up numbers, though the team is still trying to adjust to coach Mike Brown's system.

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Minnesota Timberwolves vs. New York Knicks Preview, Odds, Betting Tips and Prediction

Moneyline: Timberwolves (+170) vs. Knicks (-205)

Spread: Timberwolves +5.5 (-110) vs. Knicks -5.5 (-110)

Total (O/U): O229.5 (-110), U229.5 (-110)

Note: The odds could change before tipoff.

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Minnesota Timberwolves vs. New York Knicks Preview

Wednesday's game is scheduled for an 8:30 p.m. EST tipoff. It will be held at Madison Square Garden in Manhattan, New York City. The game will be televised locally on FanDuel Sports Network - North in Minnesota and the MSG Network in New York City.

It's also available on ESPN, as well as live-streaming platforms like Amazon Prime Video, fuboTV and NBA League Pass, which are all require paid subscriptions.

The Timberwolves have a record of 4-3, putting together a mix of dominating and disappointing performances. They lost Nickeil Alexander-Walker in free agency, with the rest of the bench corps still trying to find the right player who could fill in the role.

Meanwhile, the Knicks also have a record of 4-3 after the first two weeks of the campaign. It's all about making the right adjustments to Mike Brown's offense, especially after coming off a different kind of playbook under former coach Tom Thibodeau.

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Minnesota Timberwolves vs. New York Knicks Predicted Starting Lineups

Timberwolves

G - Mike Conley | G - Donte DiVincenzo | F - Jaden McDaniels | F - Julius Randle | C - Rudy Gobert

Knicks

G - Jalen Brunson | G - Landry Shamet | F - Miles Bridges | F - OG Anunoby | C - Karl-Anthony Towns

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Minnesota Timberwolves vs. New York Knicks Betting Tips

Anthony Edwards is questionable for the game, but the latest odds have him playing and predicted to go over 25.5 points.

Jalen Brunson is favored to go under 27.5 points despite averaging 29.0 points per game this season.

On the other hand, Karl-Anthony Towns has an over/under of 22.5 points, which is hard to gauge since he's against his former team.

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Minnesota Timberwolves vs. New York Knicks Prediction

The Timberwolves are the slight underdogs in Wednesday's matchup against the Knicks. Both teams enter on two-game winning streaks, with one surely ending. The prediction is a win for the Knicks, with the total going OVER 229.5 points.

Edited by Juan Paolo David