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Liverpool ended their four-game losing streak in style as Arne Slot's reshaped side stormed to a 5-1 UEFA Champions League win at Eintracht Frankfurt in midweek.
Defeats to Crystal Palace, Galatasaray, Chelsea and Manchester United had set an unwanted career record for the Dutchman, but the Premier League champions rallied in Germany.
A return to Premier League action gives Slot a chance to use that positive winning momentum to exert pressure on leaders Arsenal, but he faces a few selection calls ahead of the trip to Brentford on October 25.
His call to drop Mohamed Salah from the starting XI in Frankfurt created headlines and the decision was bolstered by a dominant away win.
Keith Andrews has been praised for a positive start at Brentford after replacing Thomas Frank over the summer, and the Bees have lost just one home game under the Irishman this season.
MORE: Alexander Isak's injury delays Liverpool's 'impossible' Mohamed Salah decision
Liverpool lineup vs. Brentford: Projected starting XI
Mamardashvili (GK)
Bradley, Konate, Van Dijk, Kerkez
Mac Allister, Szoboszlai
Salah, Wirtz, Gakpo
Ekitike
Formation: 4-2-3-1
Liverpool team news
With Alisson still sidelined, Slot will continue with Giorgi Mamardashvili in goal, but there will be changes to the defence ahead of him.
Jeremie Frimpong was forced off early on against Frankfurt, and Conor Bradley is expected to replace the Dutch international, while Milos Kerkez should rotate in at left-back for Andy Robertson.
Slot opted against risking Alexis Mac Allister from the start in Frankfurt, but he's fully recovered from a head injury sustained in the United loss and could come back in.
The main call for Slot focuses on what to do with Salah as he boldly benched the Egypt international in midweek.
Despite indicating his confidence in Alexander Isak's latest injury not being too serious, Slot is wary of starting him in successive games and risking his delicate fitness. That could offer Salah a route back into the team, but it could mean a formation change, with Isak kept in reserve on the bench.
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Liverpool injury list
Below is the latest injury picture for Liverpool, including estimated return dates for those who are sidelined.
Giovanni Leoni
- Injury: Anterior cruciate ligament (ACL) tear
- Expected return date: August 2026
Summer signing Leoni suffered a nightmare debut as he horrifically tore an ACL in the EFL Cup win over Southampton. The Italian defender underwent immediate surgery and his campaign has already been cruelly ended.
Alisson Becker
- Injury: Thigh
- Expected return date: November 2025
Slot's No. 1 Alisson suffered a thigh injury saving a certain goal in the defeat to Galatasaray at the end of September. The summer departure of Caoimhin Kelleher to Brentford was instantly filled by Mamardashvili, with Slot under no pressure to rush his first-choice keeper back. He could be out until December.
Jereme Frimpong
- Injury: Hamstring
- Expected return date: November 2025
Frimpong suffered the second hamstring injury of his early Liverpool career in Frankfurt and faces another month on the sidelines as club medics look to get to the bottom of a nagging issue for the former Bayer Leverkusen star.
Ryan Gravenberch
- Injury: Ankle
- Expected return date: October 2025
Gravenberch was forced off against United and Slot left him behind on Merseyside for the trip to Frankfurt. The Reds boss claimed he is hopeful of his participation against Brentford, and he could make the squad if passed fit.
Alexander Isak
- Injury: Groin
- Expected return date: October 2025
Slot was keen to play down concerns over his No. 9 after being forced to replace him in Frankfurt. The decision to bring him off at halftime was a precaution, but no risks will be taken on the Premier League's most expensive player, and he could drop to the bench.
Brentford vs. Liverpool match details
- Date: Saturday, October 25, 2025
- Kickoff time: 8 p.m. local / 3 p.m. ET / 12 p.m. PT / 6 a.m. AEDT (Oct. 26)
- Location: Gtech Community Stadium, London (England)
- Competition: Premier League matchweek nine
- Referee: Simon Hooper
- VAR: John Brooks
English (US)