Galderma Tackles Menopause-related Skin Changes With Global Survey and Clinical Trial Inclusivity

• Results from a global survey of over 4,300 women across five continents presented at IMCAS 2026 reveal a knowledge gap on the impact of menopause on the skin, despite women experiencing around three skin changes during menopause¹
• Galderma will also host a symposium delving into the challenges and science behind menopause-related skin changes and aesthetic solutions at the congress
• Galderma is committed to raising awareness of the impact of menopause on the skin, fostering meaningful dialogue between patients and healthcare professionals, and advancing science-backed solutions by incorporating menopausal status into all injectable aesthetics clinical trials

Menopausal women experience a decline in estrogen, which supports many aspects of skin health, with fluctuations starting in the peri-menopausal stage.^4,5 Decreasing estrogen leads to an expedited decline in collagen and elastin, with a 30% reduction in collagen seen within the first five years post-menopause, causing the skin to lose firmness and be more prone to wrinkles.^4-6 It also decreases the hyaluronic acid levels in the skin, which can result in dehydration, dryness, and itchiness.⁴ Often not very well-known and understood, the effects of menopause on the skin are frequently overlooked but can negatively impact wellbeing.^2,7,8 Galderma’s survey found that women agreed or strongly agreed that menopause-related skin changes made them feel less attractive (60%), anxious (57%), less confident (55%), and want to socialize less (46%).¹ Aesthetic treatments can help to address this by targeting the root causes and correcting these skin changes for an enhanced look, and as a result, can boost confidence and positive self-perception.^4,5

Global findings highlight the unspoken struggles of skin changes during menopause
Galderma’s survey presented as a poster at IMCAS included more than 4,300 peri- and post-menopausal women aged 45-60 from the United States, Brazil, Germany, the United Kingdom, Saudi Arabia, United Arab Emirates, Egypt, China, and Thailand, who have had or would be open to aesthetic treatments.¹ Results showed:

• The women surveyed experienced an average of three skin changes to the face and body since the start of menopause.² The main changes were lines and wrinkles (experienced by 59% of women on the face and 33% on the body), loss of firmness and elasticity (58% on the face and 54% on the body), increased dryness (56% on the face and 58% on the body) and a duller skin tone (40% on the face and 30% on the body).¹
• The overall impact of skin changes on the face and body was rated six out of ten in severity.²
• Of all the treatments or actions to help reduce the effects of menopause – such as cognitive behavioral therapy, exercise changes, food supplements and traditional medicine – aesthetic treatments had the highest level of satisfaction with results.²
• Many women said they would consider aesthetic treatments in the future to help with menopause-related skin changes: 47% would consider anti-wrinkle treatment, 41% hyaluronic acid treatment, 39% hyaluronic acid skin quality treatment, and 30% biostimulators.²
• Currently, women primarily use aesthetics as treatment for menopause related-skin changes (49%) rather than for prevention (26%), likely because many women learned about the impact on the skin when going through the menopause, restricting the window for preventative action.² Yet, over 60% of women would have acted differently if they had known earlier about the impact of menopause on the skin.²