Countdown Awards Research Grant to Advance Mitochondrial Transplantation in Duchenne Muscular Dystrophy

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“This is exactly the kind of science we exist to accelerate, work that targets the root cause of disease at the cellular level,” said Mitzi Solomon, Founder and President of Countdown. “Muscle degeneration is one of the most visible expressions of a deeper issue: loss of cellular energy. Mitochondria are the shared engine beneath rare disease, chronic illness, and aging itself. By restoring energy at the source, we have the opportunity to fundamentally change how we treat disease and support human health.”

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“PS Cares, the philanthropic arm of PS Reserve, a private membership community centered around connection, lifestyle, and meaningful experiences, is proud to support this work,” said Jennifer Dawood, Director of Member Engagement at PS Reserve. “We are drawn to innovations that help people maintain vitality and quality of life, and our support of Countdown reflects that by funding science focused on restoring energy, resilience, and function at the cellular level. This is where we believe the future of health is headed, and we’re proud to be part of it.”

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Because mitochondrial dysfunction is a common biological thread across many conditions, the implications of this research extend far beyond Duchenne muscular dystrophy. Mitochondrial transplantation represents a mutation-independent approach. When successful, this work will establish mitochondrial transplantation as a therapeutic platform with applications across a wide range of diseases driven by impaired cellular energy, from rare genetic disorders to chronic disease and aging.

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“Our mitochondrial transplantation research would not be possible without Countdown’s support,” said Dr. James McCully. “Because of this support, we can now apply the success achieved in our pediatric cardiac clinical trial to advancing new therapies for patients who urgently need them most.”

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This investment reflects Countdown’s broader strategy to accelerate mitochondrial science as the foundation of a new era of medicine. Rather than funding individual diseases, Countdown is building a connected research ecosystem designed to accelerate diagnostics, therapies, and prevention by addressing cellular energy at its source.

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About Countdown

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Countdown is a nonprofit building a movement around cellular energy — the science most overlooked and underfunded, and most fundamental to human health. By focusing on mitochondria, the shared biological engine underlying many of the most urgent diseases of our time, we’re advancing a more integrated approach to understanding, preventing, and treating disease at its source.

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Guided by the belief that Energy Is Everything, we fund bold, high-risk, high-reward research and bring together the scientists, clinicians, innovators, philanthropists, investors, and brands advancing the future of health.

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OUR VISION

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A world where cellular energy is recognized as a foundation of human health, transforming how we understand, prevent, and treat disease while improving resilience, performance, and health across the lifespan.

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OUR MISSION

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To acceleratemitochondrial scienceand medicine and bring cellular energy to the center of human health.

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We believe the greatest breakthroughs in health will come not from any one discipline, industry, or organization, but through collaboration. By connecting people, ideas, and discovery across traditionally separate fields, we are helping accelerate scientific progress, improve health across the lifespan, and shape a new era of health rooted in the science of energy.

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Stephanie Ballien, VP of Marketing
[email protected]

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