Barcelona vs. Real Madrid prediction, odds, betting tips and best bets for Clasico title showdown in La Liga

The final Clasico of the 2024/25 campaign puts the season on the line for both sides as Barcelona host Real Madrid in Catalonia on Sunday.

With the two clubs now out of the UEFA Champions League, and nothing left to play for but the La Liga title, this match has effectively become an all-or-nothing showdown.

Barcelona come into the game with a four-point lead over second-place Real Madrid atop the table, meaning a win here all but secures them the title. Even a draw would do them well, although they'd surely prefer to seal the deal in winning fashion, especially after the disappointment suffered midweek at the hands of Inter Milan.

Madrid, meanwhile, are in a must-win situation, knowing they need to snatch three points here if they wish to have any hope of a late-season comeback against their bitter rivals.

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Barcelona vs. Real Madrid prediction, odds

• Moneyline lean: Barcelona (-110 on DraftKings)
• Score prediction: Barcelona 4-1 Real Madrid
• Best bet: Barcelona -1.5 (+205)

Everything about this game screams Barcelona multi-goal victory. There's a high likelihood that the hosts pummel their Clasico opponents.

Barcelona's recent elimination from the Champions League will have them wanting to make a statement. Hansi Flick's crazy style will have Madrid scattered. The visitors have too many injuries at the back to handle the likes of Lamine Yamal and Raphinha, while Los Blancos are too one-dimensional on the counter-attack to punish Barcelona's high defensive line.

There will be no doubt who the better side is when this match is done and dusted.

Barcelona vs. Real Madrid match facts

• Date: Sunday, May 11, 2025
• Kickoff Time: 4:15 p.m. local (10:15 a.m. ET / 7:15 a.m. PT)
• Location: Lluis Companys Olympic Stadium (Barcelona, Spain)
• Referee: Alejandro Jose Hernandez
• Last meeting: Barcelona 3-2 Real Madrid (April 26, 2025 | Copa del Rey final)

MORE: Latest team news and injury updates ahead of Barcelona vs. Real Madrid

Barcelona vs. Real Madrid best bet

• Pick: Barcelona to win both halves
• Odds: +390 (DraftKings)

Barcelona's high-octane offense means they will attack Real Madrid early and often. Madrid themselves will hope to keep a lid on the game, but that's exactly what the Catalans will want.

Barca have won five of the six halves played this season between the two clubs, only losing the second half of the Copa del Rey final (2-1) before winning in extra time.

There's an unbelievable amount of value in this play, with Barcelona at home and looking to make a season-ending statement.

Barcelona vs. Real Madrid prop bet

• Pick: Lamine Yamal 5+ total shots
• Odds: +160 on FanDuel

• Pick: Lamine Yamal to score or assist a goal
• Odds: +100 on FanDuel

Whatever Lamine Yamal's attacking odds are for this match, take them. For some reason, the market has caught up on his shot total, but not on the goal contribution front — there are still eight players considered more likely to contribute up front in this game, including, for some bizarre reason, Ansu Fati (-135).

Instead of Ferland Mendy and Antonio Rudiger on his side of the Real Madrid back line, he will be up against backup left-back Fran Garcia and natural midfielder Aurelien Tchouameni.

As the season has progressed, the teenage superstar has morphed into a high-volume, high-reward impact player with a ton of freedom. Hansi Flick has moved his attack away from Raphinha and more to Lamine Yamal, seeing a huge uptick in his shots and high-risk passes.

The kid is going to cook.