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10-12,18-20
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Sculptra progressively rebuilds the skin’s structural foundation by encouraging the remodeling of components of the extracellular matrix, such as elastin and collagen, helping to gradually restore natural volume, firmness, radiance and overall skin quality, and the look of fullness to wrinkles and folds over time.
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10-12,21-25
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Sculptra has been shown to provide visible improvements as early as one month after treatment, with results lasting up to two years.
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10,16,23,25,26
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About the Restylane portfolio
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Restylane HA treatments are designed differently to go beyond volumizing for natural-looking results.
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Our HA is minimally modified and our innovative manufacturing process preserves its biocompatibility while creating individual products designed for a specific purpose.
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Powered by NASHA
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®
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, NASHA HD™, OBT™ and SB-NASHA™ technologies, Restylane offers a range of gels from the highest firmness to the highest flexibility, enabling personalized treatments that deliver structural support, natural-looking results, and a healthy glow.
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Trusted for almost three decades, our HA gels work in sync with your skin for 100% natural-looking results.
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About Relfydess (RelabotulinumtoxinA)
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Pioneered by Galderma, Relfydess is the first and only ready-to-use liquid neuromodulator created with PEARL Technology that is designed to preserve molecule integrity.
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PEARL Technology is designed to deliver a highly active, innovative, complex-free molecule, with up to 39% of patients seeing effects from day one and up to 75% of patients maintaining improvements for six months.
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Relfydess is optimized for simple volumetric dosing, without reconstitution, to increase ease-of-use and help ensure consistent dose/volume every time.
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It was entirely created and manufactured by Galderma to expand its neuromodulator portfolio as part of the broadest Injectable Aesthetics portfolio on the market. Relfydess has received a marketing authorization in many markets. Authorization conditions vary internationally.
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About Galderma
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Galderma (SIX: GALD) is the pure-play dermatology category leader, present in approximately 90 countries. We deliver an innovative, science-based portfolio of premium flagship brands and services that span the full spectrum of the fast-growing dermatology market through Injectable Aesthetics, Dermatological Skincare and Therapeutic Dermatology. Since our foundation in 1981, we have dedicated our focus and passion to the human body’s largest organ – the skin – meeting individual consumer and patient needs with superior outcomes in partnership with healthcare professionals. Because we understand that the skin we are in shapes our lives, we are advancing dermatology for every skin story. For more information:
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References
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- Milotich A, et al. Economic potential of a next-generation ready-to-use liquid formulation of relabotulinumtoxin type A. Poster presented at AMWC 2026; March 26-28, 2026; Monaco
- Grunebaum L D, et al. RelabotulinumtoxinA treatment improved moderate-to-severe glabellar lines and lateral canthal lines regardless of baseline toxin naivety: subgroup analyses of pooled Phase 3 study data. Poster presented at AMWC 2026; March 26-28, 2026; Monaco
- Chadha P, et al. Consensus recommendations on the aesthetic use of relabotulinumtoxinA to treat upper face wrinkles. Poster presented at AMWC 2026; March 26-28, 2026; Monaco
- Fabi S, et al. Regenerative aesthetic effects of poly L-lactic acid treatment. Poster presented at AMWC 2026; March 26-28, 2026; Monaco
- Haddad A, et al. International consensus: PLLA-SCA/SB-NASHA for non-facial rejuvenation. Poster presented at AMWC 2026; March 26-28, 2026; Monaco
- Fabi S, et al. Effectiveness and safety of a hyaluronic acid skin quality injectable for the correction of wrinkles in the décolletage area. Poster presented at AMWC 2026; March 26-28, 2026; Monaco
- Ablon G, et al. A randomized, comparator-controlled trial to evaluate a hyaluronic acid filler for augmentation of the chin region. Poster presented at AMWC 2026; March 26-28, 2026; Monaco
- Nestor M, et al. Safety and effectiveness of an OBT™ hyaluronic acid filler for temple hollowing treatment: a randomized, controlled, clinical investigation. Poster presented at AMWC 2026; March 26-28, 2026; Monaco.
- Nikolis A, et al. The potential role of biostimulators/dermal fillers to address menopause-related skin conditions. Poster presented at AMWC 2026; March 26-28, 2026; Monaco
- Sculptra®. EU Instructions for Use. 2025. Available online. Accessed January 2026.
- Waibel J, et al. Bulk RNA-seq Analysis of Poly-L-Lactic Acid (PLLA-SCA) vs Calcium Hydroxyapatite (CaHA-R) Reveals a Novel, Adipocyte Mediated Regenerative Mechanism of Action Unique to PLLA. Poster presented at ASDS 2024 Annual Meeting; October 17-20, 2024; Orlando, Florida, United States.
- Waibel J, et al. Gene Analysis of Biostimulators: PLLA-SCA Triggers Regenerative Morphogenesis while CaHA-R Induces Inflammation upon Facial Injection. Poster presented at ASDS 2024 Annual Meeting; October 17-20, 2024; Orlando, Florida, United States.
- Huth S, et al. Molecular Insights into the effects of PLLA_SCA on Gene Expression and Collagen Synthesis in Human 3D Skin Models Containing Macrophages. J Drugs Dermatol. 2024;23(4):285–288. doi: 10.36849/JDD.7791.
- Galderma. Data on File. MA-46589.
- Vleggaar D, et al. Consensus recommendations on the use of injectable poly-L-lactic-acid for facial and nonfacial volumization. J Drugs Dermatol. 2014;13(4 Suppl):s44–s51.
- Widgegrow J, et al. A randomized, comparative study describing the gene signatures of poly-l-lactic acid (PLLA-SCA) and Calcium Hydroxyapatite (CaHA) in the treatment of nasolabial folds. Poster presented at IMCAS World Congress; February 1-3, 2024. Paris, France.
- Duracinsky M, et al. Safety of poly-L-lactic acid (New-Fill®) in the treatment of facial lipoatrophy: a large observational study among HIV-positive patients. BMC Infect Dis. 2014;14(474). doi: 10.1186/1471-2334-14-474.
- Zhang S and Duan E. Fighting against Skin Aging: The Way from Bench to Bedside. Cell Transplant. 2018;27(5):729–738. doi: 10.1177/0963689717725755.
- Shuster S, et al. The influence of age and sex on skin thickness, skin collagen and density. Br J Dermatol. 1975;93(6):639-43. doi: 10.1111/j.1365-2133.1975.tb05113.x.
- Zarbafian M, et al. The emerging field of regenerative aesthetics—where we are now. Dermatol Surg. 2022;48:101–108. doi: 10.1097/DSS.0000000000003239.
- Galderma. Data on File. MA-57540.
- Nikolis A, et al. A Prospective, Multicenter Trial on the Efficacy and Safety of Poly-L-Lactic Acid for the Treatment of Contour Deformities of the Buttock Regions. J Drugs Dermatol. 2022;21(3):295–303. doi: 10.36849/JDD.5924.
- Beleznay K, et al. Safety and Effectiveness of Poly-L-lactic acid (PLLA-SCA) for the Improvement in Appearance of Cellulite – A Pilot Study. Poster presented at the IMCAS World Congress; February 1-3, 2024; Paris, France.
- Mazzuco R, et al. Clinical and Histological comparative outcomes after injections of Poly-L-Lactic Acid and Calcium Hydroxyapatite in arms – a split side study. J Cosmet Dermatol. 2022;21(12):6727–6733. doi: 10.1111/jocd.15356. Epub 2022 Sep 20.
- Fabi S, et al. 24-month clinical trial data on effectiveness and safety after correction of cheek wrinkles using a biostimulatory poly-L-lactic acid injectable implant. Poster presented at IMCAS World Congress; January 26-28, 2023; Paris, France.
- Goldberg D, et al. Single-arm study for the characterization of human tissue response to injectable poly-L-lactic acid. Dermatol Surg. 2013;39(6):915–922. doi: 10.1111/dsu.12164.
- Di Gregorio C, et al. 25+ years of experience with the Restylane portfolio of injectable HA fillers for facial aesthetic treatment. E-poster presented at AMWC; March 27-29, 2024; Monaco.
- Nikolis A, et al. The role of clinical examination in midface volume correction using hyaluronic acid fillers: should patients be stratified by skin thickness? Aesthet Surg J Open Forum. 2020;2(1):1–12. doi: 10.1093/asjof/ojaa005.
- Talarico S, et al. High patient satisfaction of a HA filler producing enduring full-facial volume restoration: an 18- month open multicenter study. Dermatol Surg. 2015;41:1361–1369. doi: 10.1097/DSS.0000000000000549.
- Restylane. U.S. Instructions for use. Available online. Accessed March 2026.
- Edsman K, et al. Gel properties of hyaluronic acid dermal fillers. Dermatol Surg. 2012;38:1170–1179. doi: 10.1111/j.1524-4725.2012.02472.x.
- Galderma. Data on file. MA-58650. Degree of modification of HA fillers.
- Seo K. Facial volumization with fillers. Springer. 2021;29–83. https://doi.org/10.1007/978-981-33-6212-3_2.
- Kablik J, et al. Comparative physical properties of hyaluronic acid dermal fillers. Dermatol Surg. 2009:35S(1):302–312. doi: 10.1111/j.1524-4725.2008.01046.x.
- Galderma Data on file. MA-56724. X-strain and G’ including Shaype.
- Nikolis A, et al. Effectiveness and Safety of a New Hyaluronic Acid Injectable for Augmentation and Correction of Chin Retrusion. J Drugs Dermatol. 2024;23(4):255–261. doi: 10.36849/JDD.8145.
- Öhrlund Å et al. Differentiation of NASHA and OBT Hyaluronic Acid Gels According to Strength, Flexibility, and Associated Clinical Significance J Drugs Dermatol. 2024;23(1):1332–1336. doi: 10.36849/JDD.7648.
- Belmontesi M et al. Injectable Non-Animal Stabilized Hyaluronic Acid as a Skin Quality Booster: An Expert Panel Consensus J Drugs Dermatol. 2018;17(1):83–88.
- Solish N, et al. Dynamics of HA fillers formulated to maintain natural facial expression. J Cosmet Dermatol. 2019;18(3):738-746. doi: 10.1111/jocd.12961.
- Philipp‐Dormston WG, et al. Perceived naturalness of facial expression after HA filler injection in nasolabial folds and lower face. J Cosmet Dermatol. 2020;19(7):1600-1606. doi: 10.1111/jocd.13205.
- Shridharani SM, et al. Efficacy and safety of RelabotulinumtoxinA, a new ready-to-use liquid formulation botulinum toxin: Results from the READY-1 double-blind, randomized, placebo-controlled phase 3 trial in glabellar lines. Aesthet Surg J. 2024;44(12):1330-1340. doi: 10.1093/asj/sjae131.
- Ablon G, et al. Treatment of lateral canthal lines with RelabotulinumtoxinA, an investigational liquid botulinum toxin: clinical efficacy and safety results from the READY-2 phase 3 trial. Toxicon. 2024;237(1):107353. doi: 10.1026/j.toxicon.2024.107353.
- Relfydess®. EU Summary of Product Characteristics.
- Sundberg AL and Stahl U. Relabotulinum toxin – a novel, high purity BoNT-A1 in liquid formulation. Presented at TOXINS; January 16-17, 2021; virtual meeting.
- Do M, et al. Purification process of a complex-free highly purified botulinum neurotoxin type A1 (BoNT-A1) – relabotulinumtoxinA. Presented at TOXINS; July 27-30, 2022; Louisiana, United States.
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Contacts
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For further information:
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Christian Marcoux, M.Sc.
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Chief Communications Officer
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+41 76 315 26 50
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Richard Harbinson
Corporate Communications Director
[email protected]
+41 76 210 60 62
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Céline Buguet
Franchises and R&D Communications Director
[email protected]
+41 76 249 90 87
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Emil Ivanov
Head of Strategy, Investor Relations, and ESG
[email protected]
+41 21 642 78 12
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Jessica Cohen
Investor Relations and Strategy Director
[email protected]
+41 21 642 76 43
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