Zuckerberg, Chan shift bulk of philanthropy to science, focusing on AI and biology to curb disease

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REDWOOD CITY, Calif. (AP) — For the past decade, Dr. Priscilla Chan and her husband Mark Zuckerberg have focused part of their philanthropy on a lofty goal — “to cure, prevent or manage all disease” — if not in their lifetime, then in their children’s. But during that time, they also funded underprivileged schools, immigration reform and efforts around diversity, equity and inclusion.

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Now, the billionaire couple is shifting the bulk of their philanthropic resources to Biohub, the pair’s science organization, and focusing on using artificial intelligence to accelerate scientific discovery. The idea is to develop virtual, AI-based cell models to understand how they work in the human body, study inflammation and use AI to “harness the immune system” for disease detection, prevention and treatment.

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“I feel like the science work that we’ve done, the Biohub model in particular, has been the most impactful thing that we have done. So we want to really double down on that. Biohub is going to be the main focus of our philanthropy going forward,” Zuckerberg said Wednesday evening at an event at the Biohub Imaging Institute in Redwood City, California. Three other Biohub institutes — in New York, San Francisco and Chicago, focus on addressing different scientific challenges.

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Chan and Zuckerberg have pledged 99% of their lifetime wealth — from shares of Meta Platforms, where Zuckerberg is CEO _ toward these efforts. Since 2016, when Biohub launched, they have donated $4 billion to basic science research, a figure that does not include operating expenses for running a large-scale computer cluster for life science research. The organization says it is now on track to double that amount over the next decade, with an operating budget of about $1 billion a year.

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Last week, singer Billie Eilish told an audience that included Chan and Zuckerberg that rich people should do more to address the world’s problems.

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“Love you all, but there’s a few people in here who have a lot more money than me,” she said, to a smattering of applause. “And if you’re a billionaire, why are you a billionaire? And no hate, but give your money away, shorties.”

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The Chan Zuckerberg Initiative, the couple’s charitable organization, has been faced with criticism recently for curtailing its other philanthropic work. Earlier this year, it stopped funding grants related to diversity, equity and inclusion, immigration advocacy and other issues currently in the crosshairs of the Trump administration — though the focus has been shifting to science and away from social issues for years, the couple says, long before the 2024 election.

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“So we basically looked at the ecosystem of science funding and decided that the place that we can make the biggest impact was on tool development,” Zuckerberg said. “And specifically working on long-term projects, 10 to 15 years, where the output of them was taking on a biological challenge that would produce a tool that scientists everywhere could use to accelerate the pace of science.”