This new serum is the ‘next frontier in cellular skin rejuvenation,’ according to an expert

The fountain of youth might not be real, but the science behind Medik8‘s latest skin care launch is.

The British brand used by stars like Rosie Huntington-Whiteley and Hailey Bieber recently rolled out an advanced serum that promises to target multiple signs of aging — yet is so gentle, it can even be used post-procedure.

The new Exo-PDRN Primastic+ Youthful Vitality Serum visibly improves radiance, tone and overall skin vitality using the buzziest of clinically-backed ingredients, like a proprietary exosome complex and a vegan version of PDRN, which is typically derived from salmon sperm DNA.

Medik8 Exo-PDRN Primastic+ Youthful Vitality Serum

Medik8

Promising clinical-grade results, the Exo-PDRN Primastic+ Serum counters redness while strengthening the skin barrier and improving the look of wrinkles and sagging, all while imparting luminosity. (The before-and-after pics are impressive.)

With all the buzz around these trendy ingredients, we asked Manhattan-based Dr. Jennifer Levine for her professional perspective.

“PDRN and exosomes represent the next frontier in cellular skin rejuvenation,” the double board-certified facial plastic surgeon told Page Six Style.

“PDRN acts as a powerful biostimulator that triggers DNA repair and aggressively cuts down inflammation,” according to the anti-aging expert — making it a great choice for post-procedure, and for countering redness.

Rosie Huntington-Whiteley is a Medik8 fan. Rosie Huntington-Whiteley/Instagram

Likewise, the NYC doc shared that the exosomes deliver a concentrated cocktail “directly to cells to accelerate collagen production. Together, they reset the cellular aging clock — making them a game changer for rapid healing and long-term tissue restoration.” (Well, we’re adding to cart after this!)

On the Medik8 website, Exo-PDRN Primastic+ Serum has a near-perfect rating with nearly 1,200 reviews already.

“I’ve only been using Exo-PDRN for a week, and my skin already looks different — smoother and more radiant,” reads one.

“After several weeks of use, my skin looked brighter, smoother, and more resilient, with a noticeable improvement in overall radiance,” echoed another customer.

Scroll on to shop a few more best sellers from the brand, including Huntington-Whiteley’s go-to r-Retinoate Day & Night.

Why Trust Page Six Style Shopping

This article was written by Erica Radol, Page Six Commerce Reporter. From identifying the top anti-aging skincare secrets the stars trust to dishing on the latest fashion collabs to finding a great deal on all of the above, Erica has a knack for reporting on – and even testing – Hollywood’s bestselling fashion and beauty products. Before joining Page Six in 2025, she wrote about entertainment, lifestyle and shopping trends for Us Weekly, The Daily Beast, Entertainment Tonight, Well+Good and Hearst.