Kansas City Chiefs vs. Denver Broncos predictions, odds, and picks for Week 11 AFC West showdown

The Kansas City Chiefs will make the trip to Denver, Colorado, to face the in-form Denver Broncos. The Chiefs are 5-4 while the Denver Broncos are 8-2 entering Week 11.

With the game occurring on Sunday, November 16, 2025, at 4:25 p.m. ET, let's look at the predictions, odds, and picks for the AFC West showdown.

Kansas City Chiefs vs. Denver Broncos: Game Details

Here are the game details for the Chiefs vs. Broncos Week 11 game:

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• Date: Sunday, November 16, 2025
• Livestream: FuboTV and DAZN
• Time: 4:25 p.m. ET
• TV: CBS
• Venue: Empower Field at Mile High in Denver, Colorado

Kansas City Chiefs vs. Denver Broncos Betting Odds (via DraftKings)

• Kansas City Chiefs: -3.5, -205
• Denver Broncos: +3.5, +170
• Over: 44.5, -115
• Under: 44.5 -105

Kansas City Chiefs vs. Denver Broncos: Picks

According to CBS Sports, the Denver Broncos enter their Week 11 game against the Kansas City Chiefs with arguably the best defense in the NFL. However, the Chiefs also possess one of the stingiest defenses around.

The report states that Andy Reid has a phenomenal career record after bye weeks, with a 22-4 record. CBS Sports sees that run continuing in Week 11 and has picked the Chiefs at -3.5, with an under of 44.5.

Kansas City Chiefs vs. Denver Broncos: Prediction for Week 11

The Kansas City Chiefs are having a down year by their sky-high standards. The Chiefs have lost more games entering Week 11 than they did in the entirety of the 2024 regular season. Their typically stellar offense has shown signs of cracking in the 2025 season.

As for the Denver Broncos, the team is riding on their defense, and is one of the best placed sides to end the Chiefs' divisional dominance. Sean Payton is coaching a well-oiled machine to yet another playoff berth.

However, it's hardly a savvy move to write off Patrick Mahomes and the Kansas City Chiefs. The Chiefs typically play their best football when they're written off entering a must-win game.

The stakes are high, and when that's the case, it's tough to bet against Patrick Mahomes and Co. With that in mind, the prediction is that the Chiefs win the game by a cagey 20-17 score.

Edited by Nick Igbokwe