Jenny Mollen details ‘horror movie’ side effects of GLP-1 drug: ‘Blood everywhere’

Jenny Mollen revealed she went through a “harrowing” bloody experience while taking a GLP-1 weight loss drug that left her then-husband Jason Biggs “screaming like it’s a horror movie.”

“I was microdosing the GLPs. I was also taking other peptides,” Mollen, 47, recalled of the June 2025 incident during an appearance on Wednesday’s episode of the “Let’s Talk Off Camera With Kelly Ripa” podcast.

“But I think that something happens with your period. Maybe it’s just the perimenopausal situation.”

“Suddenly I was, like, hemorrhaging. It was, like, blood clots the size of dinosaur eggs. It was so scary,” she continued, adding that she “felt like I was laying an egg” when she went to the bathroom.

“So I run to the bathroom and I am literally sitting on the toilet and I hear this plop and just blood everywhere.”

Mollen then started “screaming” for Biggs to come assist. But, when he arrived, the “American Pie” actor, 48, joined in on her panicked moment and started “screaming like it’s a horror movie.”

Despite being rattled by the scene, Mollen didn’t immediately go to the hospital and continued “having these blood clots” at home. But, by that night, her condition worsened.

“I’m like, ‘I think I’m losing too much blood,’” she recalled telling Biggs, who was “passed out” next to her in the bed. The actor wrote off her comment, telling her “you’re fine” before closing his eyes once again.

“Meanwhile I walk to the bathroom to try to pee. I have a vasovagal reaction. I passed out on the floor,” Mollen continued. “I’m calling him. I’m like, ‘Jason, Oh, my God, I’m unconscious.’”

At which point, Biggs sprung into action and went to take Mollen to the hospital.

“I’m laid on the bathroom floor. Jason’s like, ‘Jenny you have to get up. You have to let me take you to the car. I’m going to take you to the emergency room,’” Mollen recalled.

While she “absolutely” could not walk, the author told Ripa that Biggs wanted to avoid calling an ambulance and potentially waking up their sons, Sid, 12, and Lazlo, 8.

But when she fainted a second time, Biggs called the ambulance and Mollen was taken to the hospital on a gurney.

After their hospital stay, the couple made it back home the next morning by 6 a.m. — just in time to see their son off to camp.

“That night was harrowing,” Mollen said.

Mollen was taking Tirzepatide — a GLP-1 that can regulate a person’s blood sugar, appetite and digestion, and is typically used to treat type 2 diabetes and obesity — along with a “cocktail of peptides.”

She told Ripa she was only taking the weight loss drug because she has hyperthyroid and is autoimmune.

“I don’t know if it was the GLP-1 necessarily. I think it was because I think it was messing with my hormones a little bit,” Mollen concluded. “I think had I stayed on it I would have been fine. But getting off it and then back on it is what screwed me.”