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Selection Follows Positive Phase 3 Results for Paridiprubart Demonstrating Statistically Significant Mortality Reductions in ARDS Patients
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TORONTO, March 31, 2026 (GLOBE NEWSWIRE) — Edesa Biotech, Inc. (Nasdaq:EDSA), a clinical-stage biopharmaceutical company focused on developing host-directed therapeutics for immuno-inflammatory diseases, today announced that its chief executive officer, Dr. Par Nijhawan, has been selected to deliver the inaugural presentation at the Oral Showcase at the ATS 2026 Respiratory Innovation Summit (RIS), organized by the American Thoracic Society (ATS).
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Dr. Nijhawan’s presentation will feature findings from Edesa’s Phase 3 study of paridiprubart (EB05), Edesa’s first-in-class anti-TLR4 antibody evaluated as a treatment for Acute Respiratory Distress Syndrome (ARDS), a life-threatening condition accounting for over three million ICU admissions globally each year. Edesa has recently reported two sets of Phase 3 results for paridiprubart. Initial data covered 104 patients requiring invasive mechanical ventilation (IMV). Expanded results encompass a broader 278-patient population — including both IMV and non-IMV patients — further substantiating the potential clinical benefit.
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“To be invited by experts in respiratory critical care to lead off the innovation showcase is an honor and we believe an important validation of the strength of our Phase 3 data and the potential of paridiprubart to transform treatment for patients with ARDS — a disease with few effective options today,” said Par Nijhawan, MD, FRCPC, AGAF.
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Dr. Nijhawan’s presentation is scheduled for Friday, May 15, 2026. An accompanying poster presentation by Edesa’s research team will also be featured at the RIS.
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The company also announced that Ted Steiner, MD, of the Vancouver Coastal Health Research Institute and principal investigator of the Phase 3 study, will deliver a full oral presentation of the Phase 3 results on May 20, 2026 at approximately 8:30 am ET during the ATS 2026 International Conference. The presentation, titled A Phase 3, Multicenter, Double-blind, Placebo Controlled Study of an Anti-TLR4 Antibody, Paridiprubart, in Adult Patients with Respiratory Distress on Invasive Mechanical Ventilation, will be part of the mini symposium on Immune-Endothelial Biology and Targeted Therapeutics in Acute Respiratory Distress Syndrome. Edesa’s presentation materials will be posted to the Events section of the Edesa Biotech website during the conference.
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About Paridiprubart
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Paridiprubart represents a new class of host-directed therapeutics (HDTs) that are designed to modulate the body’s own immune response when confronted with known or unknown public health threats such as novel infectious diseases as well as chemical, biological, radiological, and nuclear incidents. Importantly, HDTs are agnostic to the causal agent and can be stockpiled preemptively to respond to public health emergencies and biodefense. Mechanistically, paridiprubart inhibits toll-like receptor 4 (TLR4), a key immune signaling protein that has been shown to be activated by viruses, bacteria, injury/trauma and in the pathogenesis of chronic autoimmune diseases.
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