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Josh Allen and the Bills will host Alvin Kamara and the Saints in Week 4 of the 2025 NFL season. The AFC vs. NFC tilt will mark Buffalo's third home game of the young campaign, and, like always, tickets have been selling fast.
Reigning MVP Allen and the Bills have picked up where they left off in 2024. Buffalo opened the season with a masterful 41-40 win over Baltimore, then poured another 30 points on the Jets a week later in a 30-10 laugher. Many Bills Mafia faithful think this could finally be the year their squad pushes over the top.
The Bills went out and got better in the 2025 offseason, and they entered the campaign tied with the Ravens as +600 favorites to win the Super Bowl. They re-signed multiple key weapons. They brought in veterans in pass-catcher Elijah Moore and pass-rusher Joey Bosa. They're a force to be reckoned with, and they're once again one of the most fun teams in the NFL to watch.
BUY NOW: Get tickets to Bills vs. Saints in Week 4 of 2025 season on StubHub
Of course, the Saints also have plenty of weapons. Between veteran running back Kamara and stud wideout Chris Olave, QB Spencer Rattler has some firepower with which to work.
Ready to grab tickets to this primetime interconference showdown? Here's everything you need to know about Bills vs. Saints in Week 4, including links to the best and most affordable tickets.
Bills vs. Saints Week 4 2025 tickets
- Tickets: StubHub
Tickets for the Bills vs. Saints in Week 4 are available on StubHub.
The cheapest get-in price for this game is $319, listed as a "bestselling deal." The best deal is about $500, and the best views can be found for around $1,500.
Prices are sure to fluctuate as the game draws closer, so click the link below to view the latest costs and availability.
BUY NOW: Best prices and seats for Bills vs. Saints in Buffalo
Bills vs. Saints Week 4 2025 date, time
- Date: Thursday, Sept. 28
- Time: 1:00 p.m. ET
The Bills host the Saints in Week 4 of the 2025 NFL season. Kickoff is set for 1:00 p.m. ET on Sunday, Sept. 28 from Highmark Stadium in Orchard Park, NY.
Highmark Stadium seat map
Below is a look at the seating chart for every game at Highmark Stadium:
Ticketmaster
Buffalo Bills 2025 schedule
Here's the Bills' schedule for 2025. You can purchase tickets to any Buffalo game by clicking here.
| Week | Date | Opponent | Time (ET) |
| 1 | Sunday, Sept. 7 | vs. Ravens (SNF) | 8:20 p.m. |
| 2 | Sunday, Sept. 14 | at Jets | 1 p.m. |
| 3 | Thursday, Sept. 18 | vs. Dolphins (TNF) | 8:15 p.m. |
| 4 | Sunday, Sept. 28 | vs. Saints | 1 p.m. |
| 5 | Sunday, Oct. 5 | vs. Patriots (SNF) | 8:20 p.m. |
| 6 | Monday, Oct. 13 | at Falcons (MNF) | 7:15 p.m. |
| 7 | BYE | — | — |
| 8 | Sunday, Oct. 26 | at Panthers | 1 p.m. |
| 9 | Sunday, Nov. 2 | vs. Chiefs | 4:25 p.m. |
| 10 | Sunday, Nov. 9 | at Dolphins | 1 p.m. |
| 11 | Sunday, Nov. 16 | vs. Buccaneers | 1 p.m. |
| 12 | Thursday, Nov. 20 | at Texans (TNF) | 8:15 p.m. |
| 13 | Sunday, Nov. 30 | at Steelers | 4:25 p.m. |
| 14 | Sunday, Dec. 7 | vs. Bengals | 4:25 p.m. |
| 15 | Sunday, Dec. 14 | at Patriots | 1 p.m. |
| 16 | Sunday, Dec. 21 | at Browns | 1 p.m. |
| 17 | Sunday. Dec. 28 | vs. Eagles | 4:25 p.m. |
| 18 | Sunday, Jan. 4 | vs. Jets | TBD |
New Orleans Saints 2025 schedule
Below is a look at every game on New Orleans' 2025 schedule. Click here for tickets to every matchup.
| Week | Date | Game | Time (ET) |
| 1 | Sun., Sept. 7 | vs. Cardinals | 1 p.m. |
| 2 | Sun., Sept. 14 | vs. 49ers | 1 p.m. |
| 3 | Sun., Sept. 21 | at Seahawks | 4:05 p.m. |
| 4 | Sun., Sept. 28 | at Bills | 1 p.m. |
| 5 | Sun., Oct. 5 | vs. Giants | 1 p.m. |
| 6 | Sun., Oct. 12 | vs. Patriots | 4:25 p.m. |
| 7 | Sun., Oct. 19 | at Bears | 1 p.m. |
| 8 | Sun., Oct. 26 | vs. Buccaneers | 4:05 p.m. |
| 9 | Sun., Nov. 2 | at Rams | 4:05 p.m. |
| 10 | Sun., Nov. 9 | at Panthers | 1 p.m. |
| 11 | BYE | - | - |
| 12 | Sun., Nov. 23 | at Falcons | 4:25 p.m. |
| 13 | Sun., Nov. 30 | at Dolphins | 1 p.m. |
| 14 | Sun., Dec. 7 | at Buccaneers | 1 p.m. |
| 15 | Sun., Dec. 14 | vs. Panthers | 4:25 p.m. |
| 16 | Sun., Dec. 21 | vs. Jets | 1 p.m. |
| 17 | Sun., Dec. 28 | at Titans | 1 p.m. |
| 18 | Sun., Jan. 4 | at Falcons | TBD |
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